PARIS (AP) — John Isner has reached the second round at the French Open, defeating Jordan Thompson of Australia 6-3, 4-6, 7-6, 6-3. The 21st-seeded American hit 31 aces and converted all three of his break points.

Of the 11 men from the United States who entered the main draw at Roland Garros, only Isner and No. 25 Steve Johnson remain in the tournament. It’s the first time since 2011 that as few as two Americans got to the second round in Paris.

The other seeded American man in action Tuesday, No. 27 Sam Querrey lost to Chung Hyeon of South Korea 6-4, 3-6, 6-3, 6-3.

Among other action Tuesday:

— American Madison Keys ended a four-match losing streak by winning on clay for the first time this year, beating Ashleigh Barty 6-3, 6-2. The 12th-seeded Keys missed the first two months of this season after left wrist surgery.

— Top-seeded Andy Murray beat Andrey Kuznetsov of Russia 6-4, 4-6, 6-2, 6-0. The 2016 French Open runner-up will face Martin Klizan in the second round.

— No. 3 Stan Wawrinka had a 6-2, 7-6, 6-3 win over Jozef Kovalik of Slovakia.

— Simona Halep didn’t appear to be bothered by a recent ankle injury as the third-seeded Romanian defeated Jana Cepelova of Slovakia in straight sets, 6-2, 6-3.

— Former U.S. Open champion Juan Martin del Potro has won his first match in five years at the French Open. Playing at the clay-court major for the first time since 2012, del Potro won an all-Argentine contest against qualifier Guido Pella 6-2, 6-1, 6-4.

— Jo-Wilfried Tsonga’s first-round match was suspended because of darkness with the 12th-seeded Frenchman seemingly on the brink of an early exit. Tsonga was losing 7-5, 6-4, 6-7, 5-4 to Renzo Olivo when the match was interrupted.